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Home > Products >  Buy Lansoprazole 103577-45-3103577-45-3 Lansoprazole producer103577-45-3 in China

Buy Lansoprazole 103577-45-3103577-45-3 Lansoprazole producer103577-45-3 in China CAS NO.103577-45-3

  • FOB Price: USD: 0.26-0.40 /Metric Ton Get Latest Price
  • Min.Order: 10 Metric Ton
  • Payment Terms: L/C,T/T,MoneyGram,Other
  • Available Specifications:

    1(10-100)Metric Ton1(100-1000)Metric Ton2(1000-10000)Metric Ton

  • Product Details

Keywords

  • Buy Lansoprazole 103577-45-3
  • 103577-45-3 Lansoprazole producer
  • 103577-45-3 in China

Quick Details

  • ProName: Buy Lansoprazole 103577-45-3103577-45-...
  • CasNo: 103577-45-3
  • Molecular Formula: C21H25N
  • Appearance: crystal and powder
  • Application: chemical research
  • DeliveryTime: within 3-10 days
  • PackAge: Foil Bag or as customer's request
  • Port: Tianjin,Shanghai,or as the customer's ...
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: 99.9%
  • Storage: stay in dry, cool and well-sealed
  • Transportation: DHL TNT UPS FEDEX EMS
  • LimitNum: 10 Metric Ton
  • Moisture Content: <0.001
  • Impurity: <0.001
  • package: aluminum foil bag or as customer's req...

Superiority

 

 Lansoprazole Biological Activity

Description Lansoprazole(AG 1749) is a proton pump inhibitor which prevents the stomach from producing acid.Target: Proton PumpLansoprazole, a substituted benzimidizole proton pump inhibitor, on pharmacokinetics and metabolism of theophylline has been studied in healthy adults given oral lansoprazole 30 mg once daily for 11 days. On Days 4 and 11 of 300 mg aminophylline was simultaneously administered orally and blood samples for theophylline analysis were taken over 24 h [1]. Patients in the lansoprazole group were significantly less likely to have a recurrence of ulcer complications than patients in the placebo group (P=0.008). There was no significant difference in mortality between the two groups [2]. lansoprazole (AG-1749) and omeprazole, were found to have significant activities against this organism. The activity of lansoprazole was comparable to that of bismuth citrate, with MICs ranging from 3.13 to 12.5 micrograms/ml, and fourfold more potent than that of omeprazole [3]. Clinical indications: Duodenal ulcer; Esophagitis; Gastroesophageal reflux; Gastrointestinal disease; Helicobacter pylori infection; Peptic ulcer; Stomach ulcer; Ulcer; Zollinger-Ellison syndromeFDA Approved Date: May 10, 1995Toxicity: Symptoms of overdose include abdominal pain, nausea and diarrhea.
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Solvent
In Vitro:

DMSO : 100 mg/mL (270.74 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

In Vivo: 1.Add each solvent one by one:  10% DMSO    90% corn oil Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution 2.Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution
Solubility
1 mM 2.7074 mL 13.5369 mL 27.0739 mL
5 mM 0.5415 mL 2.7074 mL 5.4148 mL
10 mM 0.2707 mL 1.3537 mL 2.7074 mL
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
SMILES O=S(C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCC(F)(F)F)=C3C
References

[1]. Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5.

[2]. Lai, K.C., et al., Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med, 2002. 346(26): p. 2033-8.

[3]. Iwahi, T., et al., Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori. Antimicrob Agents Chemother, 1991. 35(3): p. 490-6.

Related Molecules Bafilomycin A1 | omeprazole | Vonoprazan fumarate | Zinc Pyrithione | (R)-Lansoprazole | Ilaprazole | AZD0865 | Soraprazan | bamaquimast | Esomeprazole | Esomeprazole magnesium| Chebulinic acid | Picoprazole | SKF96067 | Pumaprazole
Related Doc

SDS |COA |HNMR

*The above documents are provided by Medchemexpress and are for scientific research only.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 555.8±60.0 °C at 760 mmHg
Melting Point 178-182°C dec.
Molecular Formula C16H14F3N3O2S
Molecular Weight 369.362
Flash Point 289.9±32.9 °C
Exact Mass 369.075867
PSA 87.08000
LogP 2.76
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.635
Storage condition 2-8°C

Details

 

About us

Hebei Huanhao Biotechnology Ltd.,co is one of the most dynamic research and advanced technology companies.

We now have the most complete range of pharmaceutical intermediates.

We focus on doing forign markts and and our products sell well in many countries,such as the U.S.A, the Netherlands , Poland,Canada,England,Italy ,Columbia and so on.

We also have the business of custom synthesis of various organic compounds as a supplementary.

We can synthesis almost any chemicals. Compounds can be ordered in scales ranging from milligrams to tons.

Welcomed the new and old customers advisory purchase.

 

 

Basic information

Product Name:

1-Phenyl-2-nitropropene

Synonyms:

(2-Nitro-1-propenyl)benzene;(2-Nitropropenyl)benzene;[(1E)-2-Nitro-1-propenyl]benzene;1-(2-nitropropenyl)-benzen;1-(2-Nitropropenyl)benzene;1-Phenyl-2-nitro-1-propene;1-Phenyl-2-nitro-propylen-(1,2);2-Nitro-1-phenyl-1-propene

CAS:

705-60-2

MF:

C9H9NO2

MW:

163.17

Product Categories:

Aromatic Hydrocarbons (substituted) & Derivatives;Acyclic;Alkenes;Organic Building Blocks;Building Blocks;Chemical Synthesis;Organic Building Blocks;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals

Mol File:

705-60-2.mol

1-Phenyl-2-nitropropene Structure

 

 

Chemical Properties

melting point

63-65 °C(lit.)

boiling point

263 °C at 760 mmHg

density

1.141 g/cm3

vapor pressure

0.0172 mmHg at 25°C

flashing point

115.7 °C

storage temp.

2-8°C

 

Usage And Synthesis

Chemical Properties

Yellow crystalline powder

Usage

Styrene derivative, with herbicide and antibacterial properties.

 
Packaging & Shipping

High Purity Benzeneacetic acid, a-acetyl-, methyl ester CAS NO. 16648-44-5

 

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