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Home > Products >  Supplier of Terbinafine HCl78628-80-5 hot sale high purity 78628-80-5

Supplier of Terbinafine HCl78628-80-5 hot sale high purity 78628-80-5 CAS NO.78628-80-5

  • FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
  • Min.Order: 10 Gram
  • Payment Terms: T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(1-100)KilogramAAAAA(1-100)Kilogram

  • Product Details

Keywords

  • Supplier of Terbinafine HCl
  • 78628-80-5 hot sale
  • high purity 78628-80-5

Quick Details

  • ProName: Supplier of Terbinafine HCl78628-80-5 ...
  • CasNo: 78628-80-5
  • Molecular Formula: C21H26ClN
  • Appearance: A white crystal powder
  • Application: collodion ,nitrocellulose, varnish,art...
  • DeliveryTime: 3 days after payment confirmation
  • PackAge: According to your request
  • Port: Shanghai
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: more than 99.6%
  • Storage: Dry and ventilated
  • Transportation: We can send it via HKems, HK Air Post,...
  • LimitNum: 10 Gram
  • Related Substances: 0.001%
  • Residue on Ignition: 0.001%
  • Heavy Metal: 0.001%
  • Valid Period: 0.001%
  • Place of origin: China

Superiority

Our company is one of the most dynamic research and advanced technology companies. We can serve well quality product and the way of our traffic is safty and efficently. For medical raw materials , for example pharmaceutical intermediates includi and synthesis of organic compounds including the Intermediates of pharmaceuticals.

    We now have the most complete range of products.We focus on doing forign markts and and our products sell well in many countries,such as the U.S.A, the Netherlands , Poland,Canada,England,Italy ,Columbia and so on.We also have the business of custom synthesis of various organic compounds as a supplementary. We can synthesis almost any chemicals. Compounds can be ordered in scales ranging from milligrams to tons.

Our goods product rapidly and safty.Samples before regular order. We focuse on serving foreign customers and our product sell well in many cuntries.We make sure the good quality product and reasonable price. We have the good after-sales service, to solve any kinds of problems, the goal is making every customer satisfy with our company and gain the best reputation.

 

Constantly strive towards 

High quality products 
Most competitive price 
Professional support 
Most effective teamwork 
Credible Cooperation 
Good after-sales work

 

We also have the business of custom synthesis of various organic compounds as a supplementary. We can synthesis almost any chemicals. Compounds can be ordered in scales ranging from milligrams to tons.

F.A.Q

1.How is the quality

The qualities of most products are above 99% purity, same are 99.7%  purity.

2.How is the package

Aluminum foil bag or as customer's required.

3.How is the storage

Keep in dry and cool place. 

4.Do I need to pay extra for shipping cost

No, our price includes the shipping cost already; you need not pay  for any tax and others.

Our Advantage:

1 high quality,competitive price,good service.

2. It's customers' right to choose the package ;

3.It's customers' right to choose the packing way for his produccts from many recent effective packing ways

4.Specials are possible when client's order is big enough, including the discount policy;

5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time

 

 

 

 

 

  • ProName: high quality of 3-[3',4'-(methyleendio...
  • CasNo: 13605-48-6
  • Molecular Formula: C9H11BrN2O5
  • Appearance: A white crystal powder
  • Application: collodion ,nitrocellulose, varnish,art...
  • DeliveryTime: 3 days after payment confirmation
  • PackAge: According to your request
  • Port: Shanghai
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: more than 99.6%
  • Storage: Dry and ventilated
  • Transportation: We can send it via HKems, HK Air Post,...
  • LimitNum: 10 Gram
  • Related Substances: 0.001%
  • Residue on Ignition: 0.001%
  • Heavy Metal: 0.001%
  • Valid Period: 0.001%
  • Place of origin: China

QUALITY ASSURANCE:

Our products are all made of purest raw materials. With high quality research lab  equipments. The facilities are beyond the competitive suppliers.

We will delivery at once your payment is check and confirmed. The delivery will be by air. will need as short as3 days to get to you. 

SAFE PAYMENT:

We accept payment of PAYPAL/ West Union/ Money Gram. All is for your convenient. So your  payment is ensured. Please don't hesitate to buy form us.

LOWEST PRICE:

We have very good price because of our advanced technology and huge supply of products. But  we accept test samples in very low price.

Time is money,Contact us talk more privacy Drugs .

1:Safe shipping (TNT;EMS;FEDEX;DHL;UPS;EUB)

2:Safe payment(Btc;MoneyGram;WU)

3:Safe packing (Paraffin coating; Double aluminum foil bag; Vacuum packaging)

4:Fast delivery (3-10 DAYS fast home delivery service )

5:Best quality (Without any doping, all products are pure)

6:Safety guarantee (we do this business long time ,we know how to disguise let the product through customs)

8:New international transportation system(Pls see the pic,The transportation line reaches every corner of the world)

9:Huge Supply(We have many raw materials and processing centers,Each day can provide dozens of kilogram-hundreds of kilograms of different products.)

10:Low Price(All the products are factory prices it can let you have a bigger profit margin)

11:Welfare of member(We will provide all kinds of benefits to you when you become our member)

12:Ensure the privacy of customer information(No one knows where you are and who are you)

Details

 terbinafine hydrochloride Biological Activity

Description Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM.
Related Catalog
Target

Ki: 30 nM (squalene epoxidase)[1]

In Vitro Terbinafine has a primary fungicidal action in vitro against most fungal pathogens, including dermatophytes, and dimorphic and filamentous fungi. Terbinafine specifically inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation. The treated fungal cells rapidly accumulate tlic intermediate squalene and become deficient in the end-product of the pathway, ergosterol[1].
In Vivo Terbinafine is not only active after topical application but is very effective in experimental dermatophytoses following oral administration. In fungi infected guinea-pigs, the skin temperature dropps dramatically after the fourth treatment of terbinafine[2].
Solvent
In Vitro:

10 mM in DMSO

Solubility
1 mM 3.0498 mL 15.2490 mL 30.4980 mL
5 mM 0.6100 mL 3.0498 mL 6.0996 mL
10 mM 0.3050 mL 1.5249 mL 3.0498 mL
Animal Admin Guinea-pigs: The backs (lumbar regions) of guinea-pigs, which have been mechanically depilated, are infected with 0.1 mL Sabouraud's dextrose 2% broth containing 106 c.f.u. of Truhophyton mentagrophytes. The treatments commence 48 h post-inoculation. The test compounds (Terbinafine) are suspended in 2% tylose and Tween 80 and administered via a stomach tube once daily on 9 consecutive days, or dissolved in a mixture of polyethylene glycol 400 and etbanol and spread on the infected part ot the body in a volume of 0.4 mL with a Hrigalski spatula once daily for 1-7 consecutive days[2].
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping Room temperature in continental US; may vary elsewhere
SMILES CN(C/C([H])=C([H])/C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C21.[H]Cl
References

[1]. Ryder NS, et al. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol. 1992 Feb;126 Suppl 39:2-8.

[2]. Mieth H, et al. Preclinical evaluation of terbinafine in vivo. Clin Exp Dermatol. 1989 Mar;14(2):104-8.

Related Molecules Cycloheximide | Hygromycin B | Cancidas | 5-Flucytosine | Posaconazole | Terbinafine | Ciclopirox | Isavuconazole | Anidulafungin | Clotrimazole | Clioquinol | Miconazole Nitrate | Natamycin | Ascomycin | Econazole (nitrate)

 Chemical & Physical Properties

Density 1.007g/cm3
Boiling Point 417.9ºC at 760 mmHg
Melting Point 204-208°C
Molecular Formula C21H26ClN
Molecular Weight 327.891
Flash Point 183.7ºC
Exact Mass 327.175385
PSA 3.24000
LogP 5.67930
Index of Refraction 1.586
Storage condition -20°C Freezer

 

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